1. Each of these genes could offer a point at which to disrupt the angiogenesis induced by tumors. 2. It was this observation that led him to suppose that growing tumors must induce their own blood supply, probably through secreting some factor into the surrounding tissue. 3. Normally the tumors induce blood vessels to grow toward them from the cornea, but when shark cartilage was present, the scientists found remarkably little capillary growth. 4. The finding could be important for cancer therapy, because solid tumors must induce new blood vessels to form around them when they grow beyond a certain size. 5. The question Folkman asked was, how do tumors induce the body to send out new capillaries? 6. To grow beyond a certain size, tumors must induce a nearby blood vessel to sprout new branches that will supply them with oxygen and nutrients. 7. Tumors must induce the body to form a blood supply to them. |