1. Cancer vaccines can cause an advanced tumor to shrink while patients with a poor prognosis can remain in remission. 2. And one patient had a partial response, meaning that a sizable tumor shrank. 3. At first, the tumors shrank when their blood supply was cut off and then they grew back when endostatin was stopped. 4. But both of those scenarios assume that the FDA will be satisfied by evidence that tumors are shrinking, since that can be seen within months. 5. He noted that he began to feel better, and for a time his tumors shrank. 6. He prescribed indomethacin, an anti-inflammatory drug that often makes such tumors shrink. 7. In addition, preliminary results showed that eight of nine patients with tumors containing the active growth factor either saw their cancer stabilize or tumors shrink, ImClone said. 8. In patients who get IntraDose, tumors should shrink in size. 9. In the five others still alive, tumors have shrunk by more than half. 10. In three patients, the treated tumors had shrunk, and in three others the tumors had stopped growing. |