1. For positive controls, sections containing rectal carcinoma and normal mucosa were employed and for negative controls the primary antibodies were excluded. 2. Also with respect to tissue type plasminogen activator, antigen and activity were in general significantly correlated in carcinomas and normal mucosa. 3. This is similar to the rate for normal mucosa obtained here, but with more interindividual variation. 4. Furthermore, experimental studies have investigated cell kinetics in normal mucosa and in benign and malignant tumours of the human colon by labelling with bromodeoxyuridine. |