41. Those who inherit two copies of the mutated gene get a potentially deadly disease. 42. Using a new laboratory technique called reverse genetics, they were able to pinpoint two mutated genes in the lethal strain. 43. Women with a family history of breast cancer are most likely to have a mutated BRCA gene if the cancers in their blood relatives occurred before menopause. 44. A mutated gene can create an abnormal protein, setting off a chain reaction that ends in disease. 45. Another inevitable situation is the inheritance of the mutated gene from the parents. 46. Blanka Rogina, a co-author of the study, said female flies with the mutated genes were able to reproduce throughout life. 47. Children need to inherit just one copy of the mutated gene from one parent to have autism. 48. Four of the obese people carried the mutated gene, but none of the normal-size people had it. 49. He and colleagues reported that the mutated gene gives the parasites varying resistance to five drugs. 50. He said it may be possible to develop a drug that inhibits metabolism in the same way as the mutated Indy gene. |