1. As the mutated cell remains in the bloodstream, it may accumulate other mutations and eventually pile up enough errors in its genetic material that it becomes cancerous. 2. Conventional theory holds that the mutated cells compete for the antigen held hostage. 3. Gilman then showed that the mutated cells lacked the transducer function. 4. He said he found the same mutated cells a year later when he looked again at blood from the same people. 5. Next, the mutated B cells move into the light zone, Kelsoe said. 6. These mutated cells, in low-oxygen conditions, have an enormous competitive advantage and soon dominate in the central regions of solid tumors. 7. They roam the body on search-and-destroy missions, looking for infectious organisms and mutated cells. |