1.   Are gene defects relevant at all?

2.   In familial cases without a gene defect regular echocardiograms are the only practicable screening method.

3.   Recent work suggests that correction of any one tumour suppressor gene defect is suficient to inhibit tumorigenicity, even in the presence of several other abnormalities.

4.   This susceptibility is not caused by a single gene defect but is thought to result from the cumulative interaction of a number of genes.

5.   FAMILIES with a history of both breast and ovarian cancer have the same inherited gene defect, scientists announced yesterday.

6.   But embryonic stem cells could well be a better vehicle for gene insertion to correct inherited gene defects.

7.   But even the single gene defects more common in sperm can have large consequences.

8.   But ultraviolet is potent enough to trigger the chemical transformations that lead to mutations and gene defects.

9.   He said the next step is to begin looking for a corresponding gene defect in people.

10.   His electrocardiogram showed long-QT syndrome, and genetic testing revealed a gene defect known to cause the heart problem.