1. An account of the development of behaviour within an individual would have to mention a series of environmental influences on gene expression. 2. Similar effects on limb outgrowth and Hoxd gene expression were observed in forelimb cultures. 3. There is indeed direct evidence that mechanical stress can generate intracellular signals that regulate gene expression. 4. We propose that in Raji cells the accumulation of a repressor is prevented, thus allowing gene expression. 5. Is there then a single component contained within the EHS substratum that interacts with the hepatocyte to affect specific gene expression that is missing from plastic or simple substrata? 6. The specificity of the interaction observed with the SSB oligonucleotide and the possible formation of the cruciform structure indicate a role for this element in regulating gene expression. 7. The process of gene expression is dependent upon the localised melting of the DNA double helix to expose the single strand template during transcription. 8. They exhibit a number of interesting and often novel mechanisms of gene expression and control, such as RNA editing, transsplicing and polycistronic transcription. 9. As a physician and molecular biologist researching gene expression at the National Institutes of Health, he was harvesting immature eggs from Xenopus ovaries. 10. Biologists can now hope to understand many diseases at the level of the human cell by comparing gene expression in normal and diseased tissue. |
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