1. And he had pancreatic cancer, which he cursed because it prevented him from drinking port and eating ice cream. 2. In her late fifties, she lay in the hospital bed with a rapidly progressing pancreatic cancer. 3. Pancreatic cancer cell lines overexpress epidermal growth factor receptors and also have the capacity to produce transforming growth factor, the altrnate agonist of the EGF receptot. 4. The purpose of this study was to determine if TGF had a trophic effect on the growth of pancreatic cancer in vivo. 5. Korc and colleagues have shown that human ductal pancreatic cancer cell lines may overexpress the receptors for epidermal growth factor. 6. The growth of established pancreatic cancers is promoted and pancreatic carcinogenesis is accelerated by EGF in animal mdels. 7. The purpose of this study was to examine the effect of TGF on the growth of hamster ductal exocrine pancreatic cancer cells in vivo. 8. This study clearly shows that like EGF, TGF will stimulate the growth of ductal exocrine pancreatic cancer in vivo. 9. Results by origin of tumour show that one third of patients with cholangiocarcinomas and one quarter of those with pancreatic cancer were positive on cytology. 10. Diagnosis of pancreatic disease was made by both computed tomography and endoscopic retrograde cholangiopancreatography in all patients and documented at laparotomy in those with pancreatic cancer. |
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