1.   Experts call the insecticides a major advance and say Phoenix-area residents can expect a dramatic Decline in the whitefly population this fall.

2.   It was named enkephalin and its discovery was a major advance in the search for new analgesics.

3.   Major advances in overcoming this difficulty have been made by using antibodies to distinguish between cells that seem very similar.

4.   That is a major advance in the concept of public service of which the Government are rightly proud.

5.   The film Marks a major advance in complexity in terms of both characterization and narrative structure.

6.   There is no doubt that this new type of tyre represents a major advance in road safety.

7.   We view skin-to-skin care as a major advance in helping parents develop a closer tie to their infant.

8.   Researchers have announced a major advance in the treatment of cancer.