1. Carcinogenesis in the human colon is associated with a marked increase of urokinase type plasminogen activator and a decrease of tissue type plasminogen activator. 2. Furthermore, experimental studies have investigated cell kinetics in normal mucosa and in benign and malignant tumours of the human colon by labelling with bromodeoxyuridine. 3. Furthermore, the higher concentrations used in this study reflect total bile salt concentrations in human colon. 4. The magnitude of the rise in circulating PYY concentrations after deoxycholate perfusion in the human colon was similar to the rise reported after a normal meal. 5. It allows the study of regional transit of solids in the unprepared human colon without the need for colon intubation. 6. Furthermore, the electrophysiological properties of the colonic circular muscle of the cat and dog are very different from that of the human colon. 7. This experiment shows a previously unknown dietary effect upon bacterial activity in the human colon. 8. Contrary to our expectations, PABA that was instilled into the human colon was recovered well from urine. |