71.   This is because this analysis excludes the effect of changes in basal acid secretion, which is thought to be independent of gastrin dependent.

72.   We have also shown for the first time such treatment also decreases basal gastric acid secretion significantly.

73.   Thus H pylori infection combined with active ulceration may cause the increased basal acid secretion seen in duodenal ulcer disease.

74.   The fall in basal acid secretion found may not necessarily be due to the eradication of H pylori.

75.   We measured circulating gastrin to determine the concentrations of gastrin required to produce half maximal acid secretion.

76.   There has been debate as to whether this should be calculated with or without subtraction of basal acid secretion.

77.   It is widely held that the increased basal acid secretion in patients with duodenal ulcer disease is determined by vagal drive rather than circulating gastrin.

78.   Gastric intubation studies of seven healthy adult volunteers showed a direct relation between changes in gastric acid secretion and changes in urine acid output.

79.   Children who are malnourished with chronic diarrhoea have defective gastric acid secretion.

80.   Population studies of gastric acid secretion in children at risk from undernutrition are clearly not possible using conventional intubation techniques.