31. One of these presented with a perforated small bowel lymphoma and died shortly after diagnosis. 32. A plain supine abdominal radiograph showed gaseous dilatation of the transverse colon and small bowel. 33. The small bowel mesentery was thickened and contained multiple enlarged lymph nodes. 34. This patient presented with malabsorption and small bowel biopsy specimens were consistent with a diagnosis of coeliac disease. 35. Clearly the combination of malabsorption with small bowel villous atrophy and lymphocytic inflation is not specific for coeliac disease because EATCL may present in similar fashion. 36. Small bowel biopsy and abdominal computed tomography are essential but often unhelpful in early diagnosis. 37. Comprehension of stem cell biology of specific tissues has aided development of the above methods and may be approporiate for development of similar techniques, for the small bowel. 38. The small bowel mucosa has distinct proliferative and functional epithelial cell subpopulations. 39. Data relating to morphogenesis by small bowel isolates of later development, are limited. 40. An enzymatic method for isolation of small bowel epithelium and successful establishment of primary cell culture from the normal postnatal small intestine has recently been described. |
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