11.   This treatment represents a significant advance in the field of cancer research.

12.   Despite significant advances in family planning, the report said, birth control had become a matter of global survival.

13.   Materials Technology Division showed significant advances over last year which are particularly gratifying given the management attention focused on this business.

14.   Historians working on the history of crafts, trades, housing and furniture have also made significant advances in their subject by using probate inventories.

15.   Analyst Bill Pecoriello of Sanford Bernstein believes the stock will start making significant advances in the second quarter.

16.   Analysts said the tiny device may represent a significant advance in drug-delivery technology, one that could be used for other eye conditions as well.

17.   Analysts say any significant advances in browser technology produced through a relatively public medium like a Web site also would come to the attention of Microsoft.

18.   As part of the project, DARPA scientists will have to make significant advances in miniaturizing aircraft components.

19.   Attacking cancer through new technology, changing habits, and better collaboration with industry could bring significant advances, he said.

20.   Biogen Inc. has reported a significant advance in its quest to start selling a novel treatment for psoriasis.