101.   That they have some profound effect on people sitting in the audience.

102.   The case had a profound effect on relations between the sexes in the workplace.

103.   The crimes had profound effect on the university, especially when the killer was revealed to be another freshman.

104.   The effort to cut the state portion of gas tax could have an especially profound effect on relations between states.

105.   The experience had a profound effect on the future director of American aid programs.

106.   The decision has had profound effects not only in the armed services, but in American society in general, experts say.

107.   The juice business also has had a profound effect.

108.   The lack of safe, affordable rail service between Belfast and Dublin has had a profound effect on relations between north and south.

109.   The house has had a profound effect on her consciousness.

110.   The military victories have had a profound emotional effect on Croatia.