1. A very specific antibody will be produced by the immune system for each disease to which we have been exposed. 2. Each B-cell makes its own specific antibody, depending on the type of intruder to which it is responding. 3. In patients negative to challenge there was no increase in the number of specific antibody secreting cells against beta lactoglobulin and casein. 4. The body makes a specific antibody for each disease we encounter. 5. The next step was to chemically link these highly specific antibodies to small magnetised polystyrene spheres. 6. Because of skewed distributions in immunoglobulin secreting cells and specific antibody secreting cells counts, logarithmic transformations were used. 7. A distinct rise in the number of specific antibody secreting cells to beta lactoglobulin and casein was detected in patients reacting positively to challenge in the IgM class. 8. Further evidence of immune mediation has come from the finding of circulating, non-organ specific and organ specific antibodies. 9. In patients with advanced AIDS, T gondii specific antibody secretion by PBL seems to be independent of in-vivo antigen-specific T-lymphocyte help. |
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