1.   Sometimes described as designer estrogens, the new medications must serve a dual purpose.

2.   The drug will likely be the first version of designer estrogen to reach the market.

3.   Though not ideal substitutes for the real thing, designer estrogens offer high-risk women some estrogen benefits.

4.   Like raloxifene, a designer estrogen that builds bone in menopausal women without promoting breast cancer, soy isoflavones act selectively.