1. Furthermore, a cytoplasmic anti-neutrophil antibody has also been detected in PSC and ulcerative colitis using combined indirect immunofluorescent staining with or without ELISA. 2. The present study has shown a cytoplasmic anti-neutrophil antibody, which seems to be more specific than our previously described nuclear anti-neutrophil antibody. 3. Perinuclear antineutrophil cytoplasmic antibodies have recently been demonstrated in the seaa of patients with inflammatory bowel disease. 4. The clinical significance of perinuclear antineutrophil cytoplasmic antibody positive and negative subsets in both groups of patients thus remains unexplained. 5. Antineutrophil cytoplasmic antibodies are used in diagnosing vasculitic diseases. 6. Also in patients with inflammatory bowel disease antineutrophil cytoplasmic antibodies have been detected. |
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