1. Rectal reflex contractions elicited upon distensions were detected as deflections in rectal CSA, but no clearcut relation to the distension pressure could be established. 2. Phasic rectal contraction and anal relaxation were present but exaggerated and induced at lower distending volumes than in normal subjects. 3. Rectal contractions occurred in all normal and spinal patients on ramp inflation with increasing frequency, duration, and amplitude as distension of the rectum increased. 4. Rectal contractions were associated with prolonged increases in external anal sphincter activity and anal pressure in all normal subjects. 5. In all spinal patients the distension evoked uninhibited giant rectal contractions. 6. Giant rectal contractions were never seen in normal subjects. 7. Distension of the rectum facilitates defecation in patients with complete supraconal lesions by generating rectal contractions and anal relaxations in much the same way as in normal subjects. 8. The external anal sphincter response to rectal distension is very closely associated with both rectal sensation and rectal contraction in normal subjects, and presumably acts to prevent soiling. |
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