1.   Lithocholic acid has been shown to produce DNA strand breaks and both chenodeoxycholic acid and lithocholic acid induce mitotic aneuploidy in yeast cells.

2.   The concentration of lithocholic acid was found to be higher in patients with polyps than controls as was the concentration of total secondary bile acids.

3.   A significantly higher concentration of lithocholic acid was found in polyp patients compared with controls.

4.   This may be important as lithocholic acid has been shown to be genotoxic in in vitro studies.

5.   The scientists suggested that development of a medication that acts like Vitamin D could help prevent colon cancer by helping eliminate lithocholic acid.

6.   Vitamin D helps detoxify lithocholic acid produced during digestion, researchers said.