1.   About that proposition, a large dose of skepticism is in order.

2.   Advocates say that large doses of antioxidants protect against cancer by soaking up dangerous oxygen molecules that can damage cells.

3.   In large doses it can cause nausea, vomiting, difficulty breathing and coma.

4.   In very large doses they cause stimulation of the central nervous system, convulsions and death.

5.   It appears to be almost impossible to satiate those seeking recognition in large doses.

6.   Such aggregations not only promote transmission of micro-organisms but through repeated exposure allow large doses of these.

7.   The biosynthesis of noradrenaline in the central nervous system is inhibited by large doses of benseraside.