1.   In the control group there was a significant correlation between bile acid absorption and whole gut transit.

2.   In contrast, loperamide oxide delayed both small intestinal and whole gut transit.

3.   During treatment with loperamide oxide, small intestinal transit and whole gut transit were not significantly different from the control group.

4.   Wehave shown for the first time that small intestinal and whole gut transit is faster in patients with chronic radiation enteritis.

5.   We andothers have reported that both small intestinal and total gut transit is faster in acute radiation enteritis.

6.   Loperamide oxide increased the rate of gastric emptying but slowed both small intestinal and whole gut transit.

7.   Subsequent studies confirmed that a high-fibre diet increases stool bulk and shortens gut transit.