1.   All this causes great distress through ignorance of the nature of the disease and the way it is transmitted.

2.   Although the inflammation is usually mild, on occasions it causes great distress.

3.   But while participation on business teams can offer enormous psychic satisfactions, it can also cause great distress.

4.   By nine in the evening Sarah was in great distress, as was the child within her.

5.   Her great distress really worried him.

6.   One, which caused him great distress, was that of a child.

7.   She faced the tragedy with courage, acting with dignity even though she was obviously in great distress.

8.   This negative response created great distress to Mrs X as she has her heart set on becoming an embalmer.