1.   Sensitive indicators of renal function in a group of patients maintained on long term, delayed release mesalazine and a comparable group on sulphasalazine have been studied.

2.   In this study, long term maintenance treatment with delayed release mesalazine was no more nephrotoxic than continued treatment with sulphasalazine.

3.   Delayed release mesalazine formulations release their contents rapidly in the distal small intestine and proximal colon.

4.   We have therefore studied sensitive indicators of renal function in a group of patients maintained on long term, delayed release mesalazine and a comparable group maintained on sulphasalazine.

5.   Recently, a number of cases of nephrotoxicity have been reported in patients taking delayed release mesalazine.

6.   In this study we have assessed renal function in a group of patients who have been maintained on delayed release mesalazine from six months to over six years.

7.   Some of the shortage is because of delayed releases of video games, the company said.

8.   The Commerce Department is also facing delayed releases of its economic reports, including the report on international trade in goods and services due out next Tuesday.

9.   The company attributed the decline to delayed release of new titles and weaker box office titles in current release.

10.   The Commerce Department also faces delayed releases of its economic reports, including one on international trade in goods and services due out next Tuesday.