31.   Lane has finally gotten involved in a United States-based controlled clinical trial.

32.   Months earlier, Williamson was denied entrance into a controlled clinical trial for anti-VEGF because investigators were concerned his liver was not functioning properly.

33.   Moreover, no large randomized controlled trials have determined whether the treatment reduces fractures.

34.   Nearly every controlled clinical trial of secretin has failed to show that the hormone works as claimed, Amaral said.

35.   Observational studies have suggested many health benefits from hormone replacement, but more recent controlled trials have disagreed.

36.   Researchers are surprised at that because it is rare for the results of a controlled clinical trial to translate so directly to general practice.

37.   Some women try soy protein and herbal products, but Grady said there was not evidence from controlled trials to recommend them.

38.   The debate could not be resolved because of a lack of information from scientifically controlled trials.

39.   The Israeli researchers said triptorelin needed further study because it was not tested in a controlled trial against a placebo, or dummy drug.

40.   The most scientifically sound method of determining which therapies are effective and which are not is the randomized controlled clinical trial.