11.   All subjects studied were regular smokers but the duodenal ulcer patients were significantly older and had therefore smoked for a longer period.

12.   High values of serum pepsinogen C were frequently found in all groups of patients with hyperpepsinogenaemia A.

13.   There was no significant difference in phospholipid composition between antral and duodenal sites in duodenal ulcer patients.

14.   Fifteen peptic ulcer patients who were not part of any formal trial of treatment, were referred, chiefly by surgeons presumasbly to help choose the most appropriate operation.

15.   Eradication of TH pylori lowered the plasma gastrin in the duodenal ulcer patients to values equivalent to the H pylori negative healthy volunteers.

16.   H pylori infection was confirmed in the duodenal ulcer patients by microscopic examination of antral biopsy rapid urease test on antral biopsy, and by C urea breath test.

17.   It was increased in the H pylori positive duodenal ulcer patients, however, compared with both the H pylori negative healthy volunteers and H pylori positive healthy volunteers.

18.   The median pepsin output in the H pylori positive duodenal ulcer patients was higher than both the H pylori positive and negative healthy volunteers.

19.   This study shows that chronic H pylori infection is accompanied by appreciably increased gastric acid output in both healthy volunteers and duodenal ulcer patients.

20.   The exaggerated acid response to gastrin can be explained by the increased parietal cell mass present in duodenal ulcer patients.