1.   As procedures are perfected, more patients receive them.

2.   After Frazee had perfected the procedure on baboons, Boyer was just the second of six stroke patients to undergo the operation.

3.   He had perfected the procedure by then.

4.   In fact, that hospital perfected a procedure for treating osteosarcoma later adapted for humans.

5.   The IOC had hoped to have a urine-only EPO test ready for the Winter Games but decided more time was needed to perfect the procedure.