1. In mouse experiments, endostatin has dramatically shrunk mouse tumors into invisibility and has done so without toxic effects. 2. In these models, scientists inject cells from existing mouse tumors under the skin of other mice. 3. The protein substance is so powerful, the researchers report, that a single dose curbed the growth of the mice tumors. 4. This new delivery method is a result of recent research that found mouse tumors could be shrunk with lower Endostatin doses if infusion pumps were used instead of injections. 5. When he presented a graph showing the mouse tumors growing and regressing several times and then lapsing into dormancy, there was an audible gasp, said Dr. Bouck. 6. His colleague noticed that the mouse tumor was full of blood vessels. |