1. Alcoholic beverages with low ethanol content and strong stimulants of gastric acid secretion and gastrin release, the effect of beer being equal to the maximal acid output. 2. There is no direct correlation between acid secretion and gastrin release in response to alcohol. 3. Here it is interesting to note that intrajejunal beer stimulated acid release without causing gastrin release. 4. Pure ethanol does not stimulate gastrin release in humans. 5. Their inability to stimulate gastrin release. 6. There is only one study that reports on the effect of alcohol on gastrin release in the chronic alcoholic patients. 7. In this study Hajnal et al found a noticeably impaired gastrin release in response to a meal, ethanol, and wine. 8. Abolition of the exaggerated gastrin release is probably due to an increase in the synthesis of somatostatin in the antral mucosa. |