1. In these conditions, the platelet activating factor acetylhydrolase activity which is naturally present in biopsy specimens is inactivated. 2. Stimulation with calcium ionophore increased appreciably platelet activating factor activity in lamina propria cells from all groups. 3. Oxidised LDL may also be procoagulant since it has been described as stimulating endothelial tissue factor activity and inhibiting activation of protein C. 4. Despite these tremendous advances, the authors wisely remind us that many patients with coronary disease have few or none of the known risk factors. |