1.   Interestingly, in the cholesterol gall stone patients, the nucleation time of gall bladder bile was significantly shorter compared with the corresponding value of hepatic bile.

2.   The Table shows the differences in biliary lipid composition and total protein concentration between the cholesterol gall stone patients and the gall stone free patients.

3.   The concentration of phospholipids was also higher in the cholesterol gall stone patients but not to a significant degree.

4.   The CSI in gall bladder bile of the cholesterol gall stone patients, however, was significantly greater than that of the gall stone free patients.

5.   No significant difference in total protein concentration was seen in gall bladder bile between the cholesterol gall stone patients and the gall stone free patients.

6.   Such a significant correlation, however, was absent in each bile sample taken from the cholesterol gall stone patients or gall stone free patients.

7.   When analysed separately in the cholesterol gall stone patients and gall stone free patients, there were no significant correlation of the nucleation time with the CSI.

8.   In addition, the nucleation time from more concentrated gall bladder bile has been reported to be quicker than that from hepatic bile in cholesterol gall stone patients.