1.   Any rumple would cause discomfort or pain long before the night was out.

2.   Failure of a biomaterial can at best cause discomfort to the patient and at worst can be fatal.

3.   Glare and flicker from the screen can strain eyes and poor layout of workstations can cause discomfort.

4.   If at any time any exercise causes severe discomfort, pain or extreme breathlessness, stop doing it and see your doctor.

5.   The Audit Commission must be free to cause discomfort.

6.   The procedure takes five minutes and only causes slight discomfort.

7.   Gaseous distension of the bowel causes considerable discomfort to the patient and increases transmural pressure.

8.   Although artificial implants can create breasts that appear very real, she worried that the surgery would cause discomfort or limit her in her many sports.

9.   Although these outbursts appear to have been an attempt at populism, they frequently caused official discomfort, not least because they conflicted with the Kremlin line.