31.   The additional sales of a single blockbuster drug during an extra six months without competition from cheaper generics could offset that entire investment.

32.   The agency said it considered proposing royalties on certain blockbuster drugs, but that idea was almost universally rejected by universities and the industry.

33.   The biggest star is Amgen, which uses genetically engineered bacteria to produce human proteins that are used in blockbuster drugs for kidney dialysis and cancer treatment.

34.   The company has yet to develop blockbuster drugs to replace them.

35.   The company is planning a series of blockbuster drugs as its best-selling Prilosec ulcer treatment faces competition from generic rivals, possibly this year.

36.   The larger concern about orlistat, however, is that it is not a blockbuster drug, as even its champions admit.

37.   The isolation of the epo gene put Amgen on the map, enabling the company to develop the blockbuster anti-anemia drug.

38.   The next blockbuster drug may not come to market until late next year, when Bristol-Myers is expected to introduce Vanlev, for hypertension.

39.   The profits cover the cost of finding the next blockbuster drug.

40.   The suits say that the drug companies illegally extend their monopolies on the sale of brand-name blockbuster drugs.