21.   These are profound questions for a program that is just a decade removed from a national championship and a style of play that made grown men weep for joy.

22.   This condensate is likely to help answer some profound scientific questions, and the standards institute played a crucial role in discovering it.

23.   This is a doctrine, in other words, that raises profound questions about an American culture exalting independence and self-reliance.

24.   Why did Beit Lid raise such profound questions?

25.   Behind the Israeli-Palestinian conflict lie the most profound questions about beliefs, political identity, collective fate.

26.   But in doing so he asked a profound question that all candidates, one way or another, have to answer about their ambitions.

27.   The issue, as the president noted, raises profound moral questions.