11.   The FDA sends hundreds of warning letters to companies each year, and only a small minority of them result in significant agency action.

12.   The FDA sends hundreds of warning letters to companies each year, and only a small minority of them result in substantial agency action.

13.   The FDA issues hundreds of warning letters every year only a small minority of which result in agency action.

14.   The FDA sends hundreds of warning letters to companies each year, and only a small minority of them result in substantive agency action.