1. There were no major complications in either group but minor side effects were more frequently recorded in patients on triple therapy. 2. The control group was treated with an oral triple therapy regimen which had previously been evaluated in a pilot study. 3. Because bismuth and antibiotic monotherapy fail to eradicate H pylori in an appreciable proportion of patients, triple therapy has been tried and is now the treatment of choice. 4. Patients treated with triple therapy, however, complain of considerable side effects which endangers compliance in routine clinical practice. 5. There was indeed a trend towards higher eradication rates in the triple therapy group, but this lacked statistical significance because of the rather small sample size. 6. Giving the drugs four times daily in the triple therapy group might have further improved the treatment results. 7. Triple therapy might be reserved for patients with treatment failure or with suspected penicillin hypersensitivity. |
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