1. The mechanism responsible for the inhibitory action of hyperglycaemia on gall bladder motility is not known.
2. In man, nicotine given parenterally has been shown to have an acute inhibitory action on the gastric secretion.
3. Dietary fibre may have more inhibitory actions earlier in the process.
4. Combined treatment with indomethacin and cyclosporin A did not further increase the inhibitory action of indomethacin on pancreatic eicosanoid formation.
5. Protein kinase C phosphorylates Gi and prevents its inhibitory action on the catalytic subunit.
6. This indicates that somatostatin -- and probably also octreotide -- has no direct effect on the gall bladder but exerts its inhibitory action by the myenteric plexus.
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