111.  The proposition is a difficult one even for the most skillful politician, which by most accounts the speaker is.

112.  The question of clemency for these prisoners was a very difficult one.

113.  The question of fighting police corruption is a difficult one for Giuliani.

114.  The road to wisdom is a difficult one.

115.  The transition to peace may prove a difficult one for some of these men, however.

116.  The very question continues to be an excruciatingly difficult one for American medicine to settle, in part because each doctor sees only one patient at a time.

117.  There are more difficult ones, fraught with more peril.

118.  They concede their venture is a difficult one.

119.  They will not respect you for your decision, no matter how much you assure them that it is a difficult one, but they will go along.

120.  This is the most difficult one.