1.  Except in the more extreme cases mentioned there is little or no significance in them.

2.  Extreme cases on high altitude expeditions have ended up with sleeping bags frozen solid!

3.  However, incorrect stretching can cause untold damage and even permanent injuries in extreme cases.

4.  In an extreme case, she guided one middle manager who was going through mid-life swerve into working at a zoo.

5.  In extreme cases they can suffer brain damage or die.

6.  In extreme cases you could even face prosecution.

7.  In extreme cases, it can affect our whole career progress.

8.  In extreme cases, social movement activity can turn violent and thus threaten the physical well-being of movement participants.

9.  In extreme cases, they break windows and fill the inside of the car with snow.