1.   This patient had the highest serum aspartate aminotransferase activity of the PSC patients.

2.   Serum aminotransferase activities and bilirubin concentrations were measured by autoanalyser.

3.   The reappearance of serum markers of HBV often occurred while serum transaminases activities were at or near normal.

4.   Malaise and appreciable increases in serum transaminase activities coincided with a marked increase in the number of hepatocytes staining for HDAg and also the first histological appearance of HBcAg.

5.   This was followed by a decline and then a second smaller peak in serum transaminase activities.