1.   Cyclosporin is a potent immunosuppressive agent used to prevent allograft rejection in solid organ transplantation.

2.   Cyclosporin A is a unique cyclic undecapeptide of fungal origin with potent immunosuppressive properties used to prevent the rejection of transplanted organs and to treat autoimmune diseases.

3.   Although they no longer need insulin to control their blood sugar, they now must take other drugs to prevent rejection of the transplants.

4.   Better drugs to prevent rejection and better procedures to make the operation more acceptable for donors have opened up this door.

5.   Being able to use those immune cells could also have implications for fighting infections, and for preventing rejection of transplanted organs and tissue.

6.   - Attempts to modify the immune system to prevent rejection of transplanted pancreatic islet cells to treat diabetes.

7.   A drug it developed with F. Hoffman-LaRoche proved effective in preventing the rejection of transplanted kidneys.

8.   Also, scientists have developed several drugs to suppress the immune system to prevent such rejection.

9.   But all, including Mantle, have to take cyclosporine, which prevents rejection, for the rest of their lives.

10.   But even when the immediate rejection is prevented, scientists still have to block a long-term rejection process that takes place weeks later.