1.   Another advance encouraging nicotine research is a better understanding of how the chemical works in the body, particularly in the brain.

2.   Anti-tobacco attorneys, however, contend that what Liggett knew about nicotine research and the dangers of smoking, the other tobacco companies knew as well.

3.   The papers help show that cigarette makers targeted youths and hid nicotine research, according to Tim Howard, an anti-tobacco attorney for the state of Florida.

4.   Witten also requested access to lists of documents on new product development based on nicotine research, arguing those files may contain information on spiking.