1. Bone mineral density was measured at two sites -- the left radius and the lumbar spine as described previously. 2. Each value for bone mineral density was converted to a Z-score using the reference data of Cann and Genant. 3. Each patient had three measurements of bone mineral density and rates of bone loss were estimated by linear regression for each subject. 4. The increase in both forearm and spinal bone mineral density achieved statistical significance in absolute units, percentage per annum, and also in the Z-score. 5. There was no significant correlation between the improvements in bone mineral density and the patients age or the number of years postmenopause. 6. The correlations between steroid dose and the changes in bone mineral density were not statistically significant. 7. The percentage improvement in spinal bone mineral density is similar to that reported in normal women receiving this dose of oestrogen. |