1.   Genzyme, Antigenics, and several other companies think they have made major strides with a new generation of vaccines.

2.   He has made major strides towards the top in just two years.

3.   In the past two weeks, McGarity has made major strides in that direction.

4.   Many elements are in place for women to make major strides in the workplace in the next century, according to two interesting books now out.

5.   They agreed Vrankovic had made major strides since his last visit to Boston, particularly in terms of maturity.

6.   They need to make major strides stopping the run and get improved play from all defensive linemen for their attack defense to click.

7.   Though its educational system has made major strides in the past two decades, the progress has never kept up with population growth or the needs of the economy.

8.   While soccer is still struggling to achieve major-league status as a spectator sport in the United States, the quality of play has made major strides.

9.   A test ban treaty is currently being negotiated in Geneva, where negotiators said Thursday they have taken major strides toward agreement.

10.   America Online has repeatedly insisted that it is making major strides to ensure that its real-time message service can work with those offered by other companies.