1.   Initial therapy of patients with large tumor masses has been complicated by large releases of intracellular potassium with resultant refractory hyperkalemia.

2.   As long as mice had the large tumor, they had no signs of metastases.

3.   But endostatin forces large aggressive tumors in experimental mice to shrink back down to a microscopic size at which they have no need for a private blood supply.

4.   In some instances it has made large solid tumors melt to nothing.

5.   One child had a large tumor in the area of central vision, which had to be destroyed by laser.

6.   She had a relatively large tumor in her right frontal lobe and was told by her physician husband not to read the medical literature on glioblastoma.

7.   The best that other cancer drugs have done is slow the growth of these large tumors.

8.   These findings call into question the definition of cancer, a word that historically has been used to describe a large tumor with the potential to spread and kill.

9.   When the large tumor was removed, it would no longer be a source of inhibitors, allowing the tiny metastases to proliferate.

10.   Women with large tumors usually face surgery to remove either the lump or the entire breast.