1.   Proximal migration of the fundic-pyloric junction has been documented with ageing, associated with an increase in the prevalence of chronic gastritis and gastric atrophy.

2.   The relationship between H pylori, age, and gastric acid secretion is important as H pylori infection causes active chronic gastritis which may progress to gastric atrophy.

3.   Serum gastrin concentrations may also rise with age, probably because of the increased prevalence of gastric atrophy with consequent loss of acid mediated inhibition of gastrin release.

4.   Gastritis, including the presence and severity of gastric atrophy, was assessed using the Sydney system classification and the presence of H pylori was also recorded.

5.   The prevalence of active chronic gastritis and subsequent gastric atrophy increases with age.

6.   Hypopepsinogenaemia A is often found in patients with gastric atrophy and gastric surgery.

7.   Hypopepsinogenaemia A has been found to be associated with gastric atrophy and gastrectomy.