1.   Physicians should discourage the chronic use of costly systemic drugs whose unwanted consequences may be more troublesome than IBS itself.

2.   An effective, low-cost vaccine is eagerly awaited in destitute countries that cannot afford the costly drug cocktails used to treat AIDS patients.

3.   Another hurdle is making these costly drugs available to those who need them.

4.   But because most developing nations cannot afford the costly drugs, the death rate from the disease is spiralling upward in the Third World.

5.   But most countries cannot afford the costs of such tests or to pay for the costly drugs.

6.   But recently perfected laparoscopic surgery for chronic, severe acid reflux can bring permanent relief and may be preferable to decades of costly drug therapy for some patients.

7.   Costly new drugs and rising prescription volumes account for much of the premium increases.

8.   Few can afford the costly drugs used to treat the disease in developed nations.

9.   In addition, as ever more costly drugs are introduced, prescription drug costs are rising by double digit percentages each year.

10.   Like other AIDS-drug manufacturers, it has recently been alarmed by threats from some African nations to manufacture cheap, unauthorized versions of costly AIDS drugs.