1.   However, the lack of bile flow into the intestines will result in neither urobilinogen nor urobilin being found in the feces.

2.   Bile secretion was increased in a dose-dependent fashion by intracerebroventricular neuropeptide Y.

3.   Intracerebroventricular neuropeptide Y also increased bile flow in urethane-anaesthetised rats.

4.   The demonstration of a central stimulation of alkaline bile flow suggests that bile secretion may be subject to central modulation.

5.   Bile flow was allowed to stabilise for two hours before intracerebroventricular injection of neuropeptide Y or control was given.

6.   Bile flow was collected for two hours after intraventricular injection.

7.   Intravenous infusion of neuropeptide Y for one hour did not significantly affect bile flow.

8.   In addition, if the contralateral vagus were also divided, stimulation of the proximal end of the divided vagus caused a decrease in bile flow.

9.   Centrally administered neuropeptide Y caused a dose-dependent increase in bile flow that was associated with an increase in biliary bicarbonate output.