1.   The basal gastrin concentration, however, was also proportionately lower in the present study.

2.   The mean of the three fasting samples was used as the basal gastrin concentration.

3.   Raised basal gastrin and exaggerated meal stimulated gastrin responses have been described in infected duodenal ulcer patients.

4.   Age and sex did not significantly affect basal gastrin concentrations, irrespective of H pylori state.

5.   As basal gastrin levels can be returned to normal with eradication of H pylori, the data indicate that the increase in gastrin is induced by the infection.

6.   Similar results have recently been published for basal gastrin concentrations in a small group of subjects matched for sex and age.

7.   In summary, H pylori infection is associated with increases in basal gastrin and pepsinogen-I, and pepsinogen-II concentrations.

8.   The basal gastrin value for each subject was measured by taking the mean of the three samples obtained before the start of gastrin releasing peptide infusion.

9.   In the healthy volunteers with H pylori both their basal gastrin and gastrin respose to gastrin releasing peptide were increased compared with the H pylori negative healthy volunteers.