1. Although the Scios Nova mouse develops the beta amyloid plaques, its nerve cells have not yet been shown to degenerate. 2. The adjuvant prompts the immune system to attack the amyloid plaques it would otherwise ignore. 3. The genes allow an excess accumulation of a protein called beta-amyloid, a sticky, noxious substance that forms amyloid plaques in the cerebral cortex. 4. These deposits, called amyloid plaques, are believed to cause cell death in the brain. 5. With both diseases, waxy deposits known as amyloid plaques are seen under the microscope in stricken nerve cells. 6. Most importantly, the amyloid plaques may be a byproduct of the disease, rather than the cause, Khachaturian said. 7. The studies used strains of mice that develop lots of amyloid plaques in their brains, along with measurable memory deficits, because of the genes they carry. 8. The vaccine made headlines last year when scientists reported that it largely blocks the formation of protein deposits called amyloid plaques in the brains of mice. |