71.   The main, unsolved clinical problem is chronic duodenal ulcer.

72.   There is a new animal model that seems promisingly similar to chronic duodenal ulcer in man.

73.   No other model of chronic ulcer shows such morphological and behavioural similarity to the human duodenal ulcer.

74.   Duodenal ulcer arises because aggressive forces outweigh duodenal defences and most attempts to study and treat it focus on acid-pepsin attack.

75.   The abscopal ulcer is an ideal model of acute to chronic duodenal ulcer both morphologically and in terms of its natural history of chronicity and occasional complication.

76.   The abscopal duodenal ulcer is not mediated by gastric hypersecretion of acid or pepsin.

77.   This might, at first sight, seem to reduce the validity of the model for the study of duodenal ulcer in man.

78.   There are many models of duodenal ulcer -- do we need a new one?

79.   Cysteamine has been used to induce ulcer and, although an alternative to other models, the cysteamine ulcer could not accurately represent human chronic duodenal ulcer.

80.   Models of mucosal damage in which a noxious agent such as ethanol is employed are simply not relevant to chronic duodenal ulcer.